RBRC02477

Information1

Image
BRC No.RBRC02477
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129-Grin2a<tm1Nak> Grin2b<tm1Stl> Drd2<tm1Mok> Drd3<tm1Mok> Drd4<tm1Mok>
Former Common nameB6-NR2A/NR2B/D2R/D3R/D4R KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences.
Strain descriptionNR2A (Grin2a), NR2B (Grin2b), D2R (Drd2), D3R (Drd3) and D4R (Drd4) genes multiple knockout mice.
Colony maintenance
ReferencesGenes Cells. 1(2):253-68 (1996). 9140068
J. Neurosci., 16, 7859-7867 (1996). 8987814

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Drd3dopamine receptor 316Drd3<tm1Mok>targeted mutation 1, Motoya Katsuki

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)16Grin2a<tm1Nak>targeted mutation 1, Shigetada Nakanishi

Gene symbolGene nameChr.Allele symbolAllele namePromoter
EcogptE.coli xanthine phosphoribosyltransferase16Ecogptmouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)16herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)16herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)6Grin2b<tm1Stl>targeted mutation 1, Susumu Tonegawa

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)6

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Drd4dopamine receptor 47Drd4<tm1Mok>targeted mutation 1, Motoya Katsuki

Gene symbolGene nameChr.Allele symbolAllele namePromoter
EcogptE.coli xanthine phosphoribosyltransferase7Ecogpt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)7mouse RNA polymerase II large subunit promoter

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Drd2dopamine receptor D29Drd2<tm1Mok>targeted mutation 1, Motoya Katsuki

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)9herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Information2

Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), E coli neo, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli xanthine phosphoribosyltransferase(Ecogpt), mouse RNA polymerase II large subunit promoter, mouse NMDAR2A genomic DNA, mouse NMDA2B genomic DNA, mouse Drd2 genomic DNA, mouse Drd3 genomic DNA, mouse Drd4 genomic DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Nerurosci., 16, 7859-7867 (1996).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Drs. Motoya Katsuki and Toshikuni Sasaoka is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data