Strain Information | |
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Image | |
BRC No. | RBRC02410 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6Cr-Tg(Pcdh21-creER)CYoko |
Former Common name | Pcdh21-CreER |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6NCrSlc |
Appearance | black [a/a B/B C/C] |
Strain development | Developed by Dr. Mineto Yokoi, Kyoto University Graduate School of Medicine in 2005. |
Strain description | C57BL/6Cr-Tg(Pcdh21-creER)CYoko. This transgenic mice express the tamoxifen-inducible cre recombinase gene under the control of the mouse protocadherin 21 gene promoter. This can be used to make an conditional knock-out by crossing with the other genetically-engineered mice that have floxed genes. The expression of cre recombinase was observed in mitral/tufted cells. |
Colony maintenance | Backcross to C57BL/6 (Hemizygote x C57BL/6CrSlc) |
References | Conditional genetic labeling of mitral cells of the mouse accessory olfactory bulb to visualize the organization of their apical dendritic tufts. Yonekura J, Yokoi M Mol. Cell. Neurosci., 37, 708-718 (2008). 18201899 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Esr1* | estrogen receptor 1 (ER) | UN | Esr1* | ||||
HBB2 | rabbit beta-globin intron/polyA signal | UN | HBB2 | ||||
cre | Phage P1 Cre recombinase | UN | cre | mouse Pcdh21 promoter |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | mouse pcdh21 promoter, phage P1 Cre, mouse estrogen receptor cDNA, rabbit beta-globin intron/polyA signal |
Research application | Cre/loxP system Neurobiology Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mol. Cell. Neurosci., 37(4):708-718 (2008). RECIPIENT may only use the BIOLOGICAL RESOURCE for non-commercial academic research purpose. |
Depositor | Yokoi Mineto (Kyoto University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |