RBRC02410

Information1

Image
BRC No.RBRC02410
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6Cr-Tg(Pcdh21-creER)CYoko
Former Common namePcdh21-CreER
H-2 Haplotype
ES Cell line
Background strainC57BL/6NCrSlc
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Dr. Mineto Yokoi, Kyoto University Graduate School of Medicine in 2005.
Strain descriptionC57BL/6Cr-Tg(Pcdh21-creER)CYoko. This transgenic mice express the tamoxifen-inducible cre recombinase gene under the control of the mouse protocadherin 21 gene promoter. This can be used to make an conditional knock-out by crossing with the other genetically-engineered mice that have floxed genes. The expression of cre recombinase was observed in mitral/tufted cells.
Colony maintenanceBackcross to C57BL/6 (Hemizygote x C57BL/6CrSlc)
ReferencesMol. Cell. Neurosci., 37, 708-718 (2008). 18201899

Health Report

Examination Date / Room / Rack2010/12/13Room:3-CRack:A
2010/10/18Room:3-CRack:A
2010/08/23Room:3-CRack:A
2010/06/21Room:3-CRack:A
2010/04/19Room:3-CRack:A
2010/02/22Room:3-CRack:A
2009/12/14Room:3-CRack:A
2009/10/19Room:3-CRack:A

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Esr1*estrogen receptor 1 (ER)UNEsr1*

Gene symbolGene nameChr.Allele symbolAllele namePromoter
HBB2rabbit beta-globin intron/polyA signalUNHBB2

Gene symbolGene nameChr.Allele symbolAllele namePromoter
crePhage P1 Cre recombinaseUNcremouse Pcdh21 promoter

Information2

Donor DNAmouse pcdh21 promoter, phage P1 Cre, mouse estrogen receptor cDNA, rabbit beta-globin intron/polyA signal
Research applicationCre/loxP system
Neurobiology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mol. Cell. Neurosci., 37(4):708-718 (2008).RECIPIENT may only use the BIOLOGICAL RESOURCE for non-commercial academic research purpose.
DepositorYokoi Mineto (Kyoto University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-
Genetic Background
Breeding characters

BRC mice in Publications

No Data