Strain Data Sheet

RBRC02401

Information1

Image
BRC No.RBRC02401
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129P2-Bst1<tm1Thir>
Former Common nameBST-1/CD157 KO mice
H-2 Haplotype
ES Cell lineE14.1 [129P2/OlaHsd]
Background strain
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Drs. Katsuhiko Ishihara and Toshio Hirano, Osaka University in 1997.
Strain descriptionCD157 (Bst1) knockout mice.
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6JJcl]
ReferencesJ. Immunol., 161, 3974-3983 (1998). 9780166

Health Report

Examination Date / Room / Rack2023/07/24Room:3-CRack:A
2023/04/24Room:3-CRack:A
2023/01/23Room:3-CRack:A
2022/10/25Room:3-CRack:A
2022/08/22Room:3-CRack:A
2022/07/25Room:3-CRack:A
2022/04/25Room:3-CRack:A
2022/02/14Room:3-CRack:A
2021/11/15Room:3-CRack:A

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Bst1bone marrow stromal cell antigen 15Bst1<tm1Thir>targeted mutation 1, Toshio Hirano114/A10, Bp3, Bsta1, CD157, Ly65

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)5neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Information2

Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, mouse Bst1 genomic DNA
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Immunol., 161, 3974-3983 (1998).a) The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR, Dr. Katsuhiko ISHIHARA (ishihara-im@med.kawasaki-m.ac.jp). b) RECIPIENT who wants to use the BIOLOGICAL RESOURCE for the purpose other than education and research in non-profit organization is requested to make a Material Transfer Agreement with Kawasaki medical school.
DepositorKatsuhiko Ishihara (Kawasaki Medical School)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)
Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

Wakabayashi T, Naito H, Suehiro JI, Lin Y, Kawaji H, Iba T, Kouno T, Ishikawa-Kato S, Furuno M, Takara K, Muramatsu F, Weizhen J, Kidoya H, Ishihara K, Hayashizaki Y, Nishida K, Yoder MC, Takakura N.
CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties.
Cell Stem Cell 22(3) 384-397.e6(2018) 29429943