RBRC02361

Information1

Image
BRC No.RBRC02361
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameNOD.129S2(B6)-Pdcd1<tm1Hon>
Former Common nameNOD-Pdcd1<-/-> mouse
H-2 Haplotype
ES Cell lineD3 [129S2/SvPas]
Background strainNOD/ShiJcl
Appearance
Strain development
Strain description
Colony maintenance
ReferencesProc. Natl. Acad. Sci. USA, 102, 11823-11828 (2005) 16087865

Health Report

Examination Date / Room / Rack2020/03/30Room:4-CRack:K
2020/01/27Room:4-CRack:K
2019/11/25Room:4-CRack:K
2019/09/30Room:4-CRack:K
2019/07/29Room:4-CRack:K
2019/05/27Room:4-CRack:K
2019/03/25Room:4-CRack:K
2010/04/19Room:3-BRack:J

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Pdcd1programmed cell death 11Pdcd1<tm1Hon>targeted mutation 1, Tasuku Honjo

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)1mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAmouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse PD-1(immunoglobulin superfamily member) genomic DNA
Research applicationDiabetes and Obesity Research
Immunology and Inflammation Research
Specific Term and Conditions1) The RECIPIENT shall use the BIOLOGICAL RESOURCE only for academic research for the purpose of publishing the research results.
2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR and a citation of the following literature(s) designated by the DEPOSITOR are requested. Proc. Natl. Acad. Sci. USA, 102, 11823-11828 (2005).
3) RECIPIENT shall notify the PROVIDER upon filing a patent application claiming modification of the BIOLOGICAL RESOURCE or method(s) of manufacture or use(s) of the BIOLOGICAL RESOURCE.
DepositorTasuku Honjo (Kyoto University)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved embryos (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Honjo Lab HP
Genotyping protocol -PCR-
Mouse of the Month Jul 2012

BRC mice in Publications

No Data