Strain Data Sheet

RBRC02328

Strain Information

Image
BRC No.RBRC02328
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameNOD.129X1(B6)-Fcgr3<tm1Ttk>
Former Common nameNODIII-/-
H-2 Haplotype
ES Cell lineRW4 [129X1/SvJ]
Background strainNOD/ShiJcl
Appearance
Strain development
Strain description
Colony maintenance
References
Activating Fc gamma receptors participate in the development of autoimmune diabetes in NOD mice.
Inoue Y, Kaifu T, Sugahara-Tobinai A, Nakamura A, Miyazaki J, Takai T
J. Immunol., 179, 764-774 (2007). 17617565

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Fcgr3Fc receptor, IgG, low affinity III1Fcgr3targeted mutation 1, Toshiyuki Takai
neoneomycin resistance gene (E. coli)1

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • decreased susceptibility to type I hypersensitivity reaction(MP:0005597)
    • Detailed phenotype data

    Ordering Information

    Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, mouse Fcgr3 genomic DNA
    Research applicationImmunology and Inflammation Research
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Immunol., 179, 764-774 (2007).
    DepositorToshiyuki Takai (Tohoku University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data