Strain Data Sheet

RBRC02327

Information1

Image
BRC No.RBRC02327
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameNOD.129P2(B6)-Fcer1g<tm1Rav>
Former Common nameNOD.γ-/-
H-2 Haplotype
ES Cell line
Background strainNOD/ShiJcl
Appearance
Strain development
Strain description
Colony maintenance
ReferencesJ. Immunol., 179, 764-774 (2007). 17617565
Cell, 76(3):519-29 (1994). 8313472

Health Report

Examination Date / Room / Racknull

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide1Fcer1g<tm1Rav>targeted mutation 1, Jeffrey V RavetchFce1g, FcR-gamma, FcR[g], FcRgamma, Ly-50

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)1neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Information2

Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, mouse fcer1g genomic DNA
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Immunol., 179, 764-774 (2007).
DepositorToshiyuki Takai (Tohoku University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

Zhang G, Bogdanova N, Gao T, Sheikh KA.
Elimination of activating Fcγ receptors in spontaneous autoimmune peripheral polyneuropathy model protects from neuropathic disease.
PLoS One 14(8) e0220250(2019) 31415574