BRC No.RBRC02268
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129S4-Sgcb<tm1Oza>
Former Common nameBSG-KO (C57BL/6J), B6-Sgcb KO
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Toshikuni Sasaoka, National Institutes of Natural Sciences (National Institute of Neuroscience, National Center of Neurology and Psychiatry).
Strain descriptionBeta-sarcoglycan (Sgcb) gene knockout mice. Sgcb is an integral component of the dystrophin-glycoprotein complex. Homozygous mutant mice show progressive muscular dystrophy with extensive degeneration and regeneration.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
ReferencesHum Mol Genet. 1999 8(9):1589-98. 10441321

Health Report

Examination Date / Room / Rack2009/11/09Room:4-5Rack:C


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Sgcbsarcoglycan, beta (dystrophin-associated glycoprotein)5Sgcb<tm1Oza>targeted mutation 1, Eijiro Ozawa

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)5


Donor DNAE coli neo, mouse beta-sarcoglycan (BSG) genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter)
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Hum. Mol. Genet., 8, 1589-1598 (1999).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Toshikuni Sasaoka is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data