RBRC02260

Information1

Image
BRC No.RBRC02260
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129S-Trp53<tm2Mok>
Former Common namep53KO, PFZ, PFZ632, B6-p53 KO
H-2 Haplotype
ES Cell lineCCE/EK.CCE [129S/SvEv-Gpi1<c>]
Background strainC57BL/6JJcl
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences (Medical Institute of Bioregulation, Kyushu University).
Strain descriptionp53 (Trp53) gene knockout mice (lacZ reporter).
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
ReferencesBiochem. Biophys. Res. Commun., 202, 830-837 (1994). 8048955

Health Report

Examination Date / Room / Rack2009/11/16Room:4-ARack:D
2009/09/14Room:4-ARack:D
2009/07/13Room:4-ARack:D
2009/05/19Room:4-ARack:D
2009/05/18Room:4-ARack:D
2009/03/16Room:4-ARack:D

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Trp53transformation-related protein 5311Trp53<tm2Mok>targeted mutation 2, Motoya Katsuki

Gene symbolGene nameChr.Allele symbolAllele namePromoter
lacZbeta-galactosidase (E. coli)11

Information2

Donor DNAE coli lacZ (beta galactosidase), mouse p53 genomic DNA
Research applicationCancer Research
Cell Biology Research
Fluorescent Proteins/lacZ System
Immunology and Inflammation Research
Mouse Models for Human Disease
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem. Biophys. Res. Commun., 202, 830-837 (1994).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data