RBRC02258

Information1

Image
BRC No.RBRC02258
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129S(Cg)-Grin2c<tm1Nak>
Former Common nameNR2C KO
H-2 Haplotype
ES Cell lineCCE/EK.CCE [129S/SvEv-Gpi1<c>]
Background strain
Appearance
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences (Institute of Medical Science, University of Tokyo).
Strain descriptionNR2C (Grin2c) gene knockout mice. Homozygous mutant mice are viable and fertile.
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6JJcl]
ReferencesJ. Neurosci., 16(24):7859-67 (1996). 8987814

Health Report

Examination Date / Room / Rack2008/10/20Room:3-BRack:G
2008/08/25Room:3-BRack:G
2008/06/23Room:3-BRack:G
2008/04/22Room:3-BRack:G
2008/04/21Room:3-BRack:G

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Grin2cglutamate receptor, ionotropic, NMDA2C (epsilon 3)11Grin2c<tm1Nak>targeted mutation 1, Shigetada Nakanishi

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)11herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Information2

Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), E coli neo, mouse NMDAR2C genomic DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Neurosci., 16, 7859-7867 (1996).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-
Genetic Background

BRC mice in Publications

No Data