Strain Data Sheet


Strain Information

BRC No.RBRC02227
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameICR.Cg-Ripply2<tm1.1Ysa>/YsaRbrc
Former Common namedelta-neo-Ripply2-KO
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Strain development
Strain description
Colony maintenance
ReferencesDevelopment, 134, 1561-1569 (2007). 17360776

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ripply2ripply2 homolog (zebrafish)9Ripply2<tm1.1Ysa>targeted mutation 1.1, Yumiko SagaC030002E08Rik, LOC382089

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP9loxP

Ordering Information

Donor DNAPhage P1 loxP site, mouse Ripply2 genomic DNA
Research applicationDevelopmental Biology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Development, 134, 1561-1569 (2007).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorYumiko Saga (National Institute of Genetics)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)
Saga Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

McInerney-Leo AM, Sparrow DB, Harris JE, Gardiner BB, Marshall MS, O'Reilly VC, Shi H, Brown MA, Leo PJ, Zankl A, Dunwoodie SL, Duncan EL.
Compound heterozygous mutations in RIPPLY2 associated with vertebral segmentation defects.
Hum Mol Genet 24(5) 1234-42(2015) 25343988