BRC No.RBRC02227
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameICR.Cg-Ripply2<tm1.1Ysa>/YsaRbrc
Former Common namedelta-neo-Ripply2-KO
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Strain development
Strain description
Colony maintenance
ReferencesDevelopment, 134, 1561-1569 (2007). 17360776

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ripply2ripply2 homolog (zebrafish)9Ripply2<tm1.1Ysa>C030002E08Rik, LOC382089

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP9loxP


Donor DNAPhage P1 loxP site, mouse Ripply2 genomic DNA
Research applicationDevelopmental Biology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Development, 134, 1561-1569 (2007).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorYumiko Saga (National Institute of Genetics)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-
Saga Lab HP

BRC mice in Publications

McInerney-Leo AM, Sparrow DB, Harris JE, Gardiner BB, Marshall MS, O'Reilly VC, Shi H, Brown MA, Leo PJ, Zankl A, Dunwoodie SL, Duncan EL.
Compound heterozygous mutations in RIPPLY2 associated with vertebral segmentation defects.
Hum. Mol. Genet. 24(5) 1234-42(2014) 25343988