RBRC02178

Information1

Image
BRC No.RBRC02178
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameSTOCK Cd52<tm1Osb>
Former Common nameB6;129Sv-Cd52<tm1Osb>
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development開発年:2003年、開発者:山口亮先生、岡部勝先生、機関名 大阪大学微生物病研究所129SvとC57BL/6のF1同士の交配による系統。世代数は不明。
Strain description免疫細胞、副精巣にて発現する遺伝子Cd52を欠損したアリルを持つ。ホモ個体においても妊孕性を有している。免疫関連研究への用途などが考えられる。
Colony maintenanceとくに注意すべき点はなく、通常の交配法で繁殖可能である。ホモで不妊/死亡
ReferencesGenes Cells, 13, 851-861 (2008). 18782223

Health Report

Examination Date / Room / Rack2011/06/06Room:3-2Rack:D
2011/04/04Room:3-2Rack:D
2011/02/07Room:3-2Rack:D

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Cd52CD52 antigen4Cd52<tm1Osb>targeted mutation 1, Research Institute for Microbial Diseases, Osaka University

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)4mouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele namePromoter
poly Amouse PGK poly Apoly A

Information2

Donor DNAmouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse PGK poly A signal, mouse cd52 genomic DNA
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Cells, 13, 851-861 (2008).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University (http://www.uic.osaka-u.ac.jp/en/index.html). The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.
DepositorMasaru Okabe (Osaka University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

No Data