Strain Data Sheet

RBRC02138

Strain Information

Image
BRC No.RBRC02138
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2(Cg)-Omp<tm4(cre)Mom>/MomTyagRbrc
Former Common nameOMP-Cre
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Appearance
Strain developmentDeveloped by Peter Mombaerts, The Rockefeller University in 2001.
Strain descriptionOMP (olfactory marker protein)-Cre knockin mice. An cre recombinase and neo cassette was inserted into the Omp gene. Homozygous mutant mice are viable and fertile.
Colony maintenanceHeterozygote x Wild-type [or Crossing to C57BL/6J(Crlj)]
References
Odorant receptor gene choice is reset by nuclear transfer from mouse olfactory sensory neurons.
Li J, Ishii T, Feinstein P, Mombaerts P
Nature 428, 393-399 (2004). 15042081

The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse.
Hasegawa S, Hamada S, Kumode Y, Esumi S, Katori S, Fukuda E, Uchiyama Y, Hirabayashi T, Mombaerts P, Yagi T
Mol Cell Neurosci, 38, 66-79 (2008). 18353676

Health Report

Examination Date / Room / Rack2024/05/20Room:4-ARack:F
2024/02/19Room:4-ARack:F

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frtyeast FRT (flippase recombination target) site7Frt
Frtyeast FRT (flippase recombination target) site7Frt
Ompolfactory marker protein7Omptargeted mutation 4 (cre), Peter Mombaerts
crePhage P1 Cre recombinase7creOmp
neoneomycin resistance gene (E. coli)7mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    Donor DNAphage P1 Cre recombinase DNA, yeast FRT (flipase recombination target) sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse Omp genomic DNA
    Research applicationFLP/frt system
    General Purpose
    Neurobiology Research
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior consent on use of it from Professor Peter Monbaerts, The Rockefeller University. If the RECIPIENT's research results in an invention based on the BIOLOGICAL RESOURCE, the RECIPIENT must contact DEPOSITOR to negotiate the treatment of such invention. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, the RECIPIENT must obtain a prior written consent from the DEPOSITOR. The RECIPIENT, which wishes to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research, is requested to enter into a Material Transfer Agreement with Osaka University.
    DepositorTakeshi Yagi (Osaka University)
    Strain Statusan icon for Live miceLive mice
    an icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityCryopreserved embryos (within 1 month)
    Live mouse (3 to 6 months)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)
    Lab HP (Japanese)
    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data