Strain Data Sheet

RBRC02083

Strain Information

Image
BRC No.RBRC02083
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Pcdha<tm8Tyag>/TyagRbrc
Former Common namedelta 11c2, CNR delta 11c2
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain developmentDeveloped by Takeshi Yagi, Graduate School of Frontier Biosciences, Osaka University in 2006.
Strain descriptionCNR (Pcdha) del 11-c2 mice. The region of a11 to ac2 of the Pcdha was deleted. Homozygous mice show no obvious abnormality.
Colony maintenanceHomozygote x Homozygote [or Crossing with C57BL/6J(Crlj)]
References
Total expression and dual gene-regulatory mechanisms maintained in deletions and duplications of the Pcdha cluster.
Noguchi Y, Hirabayashi T, Katori S, Kawamura Y, Sanbo M, Hirabayashi M, Kiyonari H, Nakao K, Uchimura A, Yagi T
J Biol Chem., 284, 32002-32014 (2009). 19797050

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
HcRedRed Fluorescent Protein (Heteractis crispa)18HcRed
Pcdha11protocadherin alpha 1118Pcdha11targeted mutation 8, Takeshi Yagi
loxPphage P1 loxP18loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • reproductive system phenotype(MP:0005389)
    • Detailed phenotype data

    Ordering Information

    Donor DNAPhage P1 loxP, Heteractis crispa HcRed cDNA
    Research applicationCell Biology Research
    Cre/loxP system
    Fluorescent Proteins/lacZ System
    Neurobiology Research
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. If the RECIPIENT's research results in an invention based on the BIOLOGICAL RESOURCE, the RECIPIENT must contact DEPOSITOR to negotiate. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, the RECIPIENT must obtain a prior written consent from the DEPOSITOR.
    DepositorTakeshi Yagi (Osaka University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: TBUSAMTA Nonprofit
    4. Acceptance of responsibility for living modified organism (Japanese / English)
    Lab HP (Japanese)
    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data