Strain Data Sheet



BRC No.RBRC01925
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameICR;129(Cg)-Zeb2<tm1.2Yhi>
Former Common nameSIP1 knockout mouse, SIP1Δex7, B6;129-Zfhx1b<tm1.2Yhi>
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Yujiro Higashi, Institute for Molecular and Cellular Biology, Osaka University in 2002.
Strain descriptionZeb2 (Zfhx1b) knockout mice. Homozygous mutant mice are embryonic lethal. Heterozygous mutant mice are viable and fertile, but, have a tendency to exhibit growth retardation.
Colony maintenance
ReferencesGenesis, 32, 82-84 (2002). 11857784

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Zfhx1bzinc finger homeobox 1b2Zfhx1b<tm1.2Yhi>targeted mutation 1.2, Yujiro Higashi9130203F04Rik, D130016B08Rik, mKIAA0569, SIP1, Zfx1b

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP2loxP


Donor DNAmouse zfhx1b genomic DNA, phage P1 loxP
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genesis, 32, 82-84 (2002).The RECIPIENT should consult with the DEPOSITOR in the case of application for any patents or commercial use with the results derived from the use of the BIOLOGICAL RESOURCE. The RECIPIENT should consult with the DEPOSITOR on the authorship upon publications of the results obtained from the use of the BIOLOGICAL RESOURCE. The authorship should be considered in accordance to generally accepted practices and decided through agreement between the RECIPIENT and the DEPOSITOR/DEVELOPER. The RECIPIENT of BIOLOGICAL RESOURCE should obtain prior permission from Dr. Danny Huylebroeck (Erasmus University Medical Center (Erasmus MC), The Netherlands).
DepositorYujiro Higashi (Osaka University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data