BRC No.RBRC01900
TypeTargeted Mutation and TransgeneCartagena
SpeciesMus musculus
Strain nameBOG8
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Strain development
Strain description
Colony maintenance
ReferencesInternational Immunology, 8, 297-306 (1996). 8671615
Eur. J. Immunol., 26, 2081-2086 (1996). 8814250

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Rag2recombination activating gene 22Rag2<tm1Fwa>targeted mutation 1, Frederik W Alt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)2

Gene symbolGene nameChr.Allele symbolAllele namePromoter
TCRAV8J48C1Tcra cDNA from BOG8 T cell hybridomaUNTCRAV8J48C1MMLV

Gene symbolGene nameChr.Allele symbolAllele namePromoter
TCRBV8.2DJ1.1C2Tcrb gene from BOG8 T cell hybridomaUNTCRBV8.2DJ1.1C2Tcrb


Donor DNAα 鎖遺伝子(MMLV エンハンサー&プロモーターを上流に持った V, J, C 領域を含む cDNA 2.1 kb) と β 鎖遺伝子(VDJ, C 領域を含むゲノムDNA 14.5 kb) の両者が導入されている。加えて RAG2 KO マウスとの交配により RAG2 遺伝子が欠損している。 RAG2 KO マウスは、RAG2 coding region が 1.1 kb PMC1neo/poly(A)+により置換されている。
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. International Immunology, 8, 297-306 (1996).1. Material is considered the proprietary property of Mitsubishi Kagaku Institute of Life Sciences (MITILS) and Mitsubishi Chemical Corporation (MCC).
2. Recipient Investigator agrees not to use Material for profit making or commercial purposes.
3. Recipient Investigator shall acknowledge the source of Material in any publication containing experimental results obtained with the use of Material.
4. At the conclusion of the research for which Material was requested, Recipient shall dispose of unused Material in an appropriate legal manner.
5. After providing Material, RIKEN BRC shall inform MCC of followings; names of Recipient and Recipient Investigator, purpose and date.
DepositorHajime Takayama (Mitsubishi Kasei Institute of Life Sciences)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data