Strain Data Sheet

RBRC01852

Strain Information

Image
BRC No.RBRC01852
TypeCongenic
SpeciesMus musculus
Strain nameB6.CS-Ngu1053
Former Common name
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Shigeru Tomida and Shizufumi Ebihara, Graduate School of Bioagricultural Sciences, Nagoya University. This congenic strain was produced by eight backcrossing of the region between 4/4-7 marker to D5Mit259 of CS onto the C57BL/6J.
Strain descriptionThis strain carries CS strain specific behavior (negligible immobility in inescapable situations) related loci from Chr 5 of CS backcrossed to C57BL/6.
Colony maintenance
References
Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming tests.
Tomida S, Mamiya T, Sakamaki H, Miura M, Aosaki T, Masuda M, Niwa M, Kameyama T, Kobayashi J, Iwaki Y, Imai S, Ishikawa A, Abe K, Yoshimura T, Nabeshima T, Ebihara S
Nat. Genet., 41,　688-695 (2009). 19465912

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Ngu1053Nagoya University 10535Ngu1053Nagoya University 1053

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal anxiety-related response(MP:0001362)

  • abnormal depression-related behavior(MP:0003360)

  • abnormal nest building behavior(MP:0001447)

  • improved righting response(MP:0002863)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
    The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorShizufumi Ebihara (Nagoya University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    Tomida S, Mamiya T, Sakamaki H, Miura M, Aosaki T, Masuda M, Niwa M, Kameyama T, Kobayashi J, Iwaki Y, Imai S, Ishikawa A, Abe K, Yoshimura T, Nabeshima T, Ebihara S.
    Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming tests.
    Nat Genet 41(6) 688-95(2009) 19465912