Strain Data Sheet

RBRC01821

Strain Information

Image
BRC No.RBRC01821
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Darc<tm1Skmz>/SkmzRbrc
Former Common nameDuffy (+/-) mouse
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
A role of the Duffy antigen for the maintenance of plasma chemokine concentrations.
Fukuma N, Akimitsu N, Hamamoto H, Kusuhara H, Sugiyama Y, Sekimizu K
Biochem. Biophys. Res. Commun., 303, 137-139 (2003). 12646177

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
DarcDuffy blood group, chemokine receptor1Darctargeted mutation 1, Kazuhisa Sekimizu
  • malaria, susceptibility to(MedGEN)
    • neoneomycin resistance gene (E. coli)1
  • malaria, susceptibility to(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • abnormal chemokine level(MP:0008721)

  • abnormal circulating chemokine level(MP:0010209)

  • abnormal homeostasis(MP:0001764)
    • Detailed phenotype data

    Ordering Information

    Donor DNAE. coli neo resistance gene
    Research application
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem. Biophys. Res. Commun., 303, 137-139 (2003).The RECIPIENT agrees to use the BIOLOGICAL RESOURCE only for publication of research papers.
    The DEPOSITOR should be a co-author in articles when the RECIPIENTs publish their data using these mice for 2 year after provided to the RIKEN BRC.
    The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    Transfer of the BIOLOGICAL RESOURCE to the third party from the RECIPIENT will never be done without a prior permission of the DEPOSITOR.
    DepositorKazuhisa Sekimizu (The University of Tokyo)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)
    Lab HP (Japanese)
    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data