Strain Data Sheet

RBRC01719

Strain Information

Image
BRC No.RBRC01719
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6N-Tg(AK7-LH1)/Rbrc
Former Common nameIg(H+L) Tg(AK7-LH1) mice
H-2 Haplotype
ES Cell line
Background strainC57BL/6NCrlCrlj
Appearance
Strain development
Strain description
Colony maintenance
References
Auto-reactive B cells against peripheral antigen, desmoglein 3, escape from tolerance mechanism.
Ota T, Aoki-Ota M, Tsunoda K, Simoda K, Nishikawa T, Amagai M, Koyasu S
Int. Immunol., 16, 1487-1495 (2004). 15339881

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
AK7-HUNAK7-Htransgene insertionH chain promoter
AK7-LUNAK7-Ltransgene insertionκ chain promoter

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • decreased B-1b cell number(MP:0008170)
    • Detailed phenotype data

    Ordering Information

    Donor DNAマウス免疫グロブリン重鎖染色体遺伝子、マウス免疫グロブリン軽鎖染色体遺伝子
    Research applicationMouse Models for Human Disease
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Int. Immunol., 16, 1487-1495 (2004).
    DepositorShigeo Koyasu (Keio University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)
    Lab HP
    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data