Strain Data Sheet

RBRC01656

Strain Information

Image
BRC No.RBRC01656
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Kcnh5<tm1(cre/PGR)Mim>/MimRbrc
Former Common nameEag2-hCrePR mouse
H-2 Haplotype
ES Cell line
Background strainC57BL/6NJcl
Appearance
Strain development
Strain description
Colony maintenance
References
Conditional gene targeting on the pure C57BL/6 genetic background.
Mishina M, Sakimura K
Neurosci. Res., 58 (2) 105-12 (2007). 17298852

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frtyeast FRT (flippase recombination target) site12Frt
Kcnh5potassium voltage-gated channel, subfamily H (eag-related), member 512Kcnh5targeted mutation 1 (cre), Masayoshi Mishina
PGRProgesterone receptor (human)12PGR
crePhage P1 Cre recombinase12creEag2
neoneomycin resistance gene (E. coli)12mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    Donor DNAP1 phage Cre recombinase, human Progesterone receptor (PGR) cDNA, yeast FRT (flipase recombination target) sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neomycin resistance gene, mouse Kcnh5 genomic DNA
    Research applicationCre/loxP system
    FLP/frt system
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. Prior to filing for a patent, or intellectual property or other rights based on results of research using the BIOLOGICAL RESOURCE, the RECIPIENT shall acquire the consent from the DEPOSITOR for such application. Use of the BIOLOGICAL RESOURCE shall be limited to a collaborative research. And Use of the BIOLOGICAL RESOURCE shall require co-authorship of the DEPOSITOR for TWO years after deposition of the BIOLOGICAL RESOURCE to the RIKEN BRC or for first publication if no publication is made within the TWO years.
    DepositorMasayoshi Mishina (The University of Tokyo)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data