RBRC01478

Information1

Image
BRC No.RBRC01478
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129P2-Ptprt<tm1Sata>/Rbrc
Former Common namePTP rho-1 KO/PTPRT, PTP rho KO 233
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Dr. Masanobu Satake, Tohoku University. C57BL/6 background.
Strain descriptionPTP rho, Protein tyrosine phospatase receptor type T, is a member of the receptor tyrosine phosphatase family. PTPs are signaling molecules that regulate a variety of cellular processes including mitotic cycle, cell growth, differentiation, and oncogenic transformation. At present, homozygous mutant mice show no abnormality.
Colony maintenancebackcross to C57BL/6 (Heterozygote x C57BL/6J)
References

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Ptprtprotein tyrosine phosphatase, receptor type, T2Ptprt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)2mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAmouse PTP rho genomic DNA, E. coli neo, mouse phosphoglycerate kinase promoter (PGK promoter)
Research application
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT agrees to include the DEPOSITOR as a co-author in any publications resulted by the use of the BIOLOGICAL RESOURCE during the first 2 years after deposition by the DEPOSITOR to the RIKEN BRC.
The RECIPIENT should contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE.
DepositorMasanobu Satake (Tohoku University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data