RBRC01476

Information1

Image
BRC No.RBRC01476
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameMRL.129P2(B6)-Fas<tm1Osa>/OsaRbrc
Former Common nameMRL Fas-KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Drs. Masashi Adachi and Shigekazu Nagata at Osaka University Medical School in 1995.
Strain description
Colony maintenanceBackcross to MRL/MpJJmsSlc (Heterozygote x C57BL/6NCrlCrlj)
ReferencesNat. Genet., 11(3), 294-300 (1995). 7581453

Health Report

Examination Date / Room / Rack2008/07/14Room:4-BRack:B
2008/05/20Room:4-BRack:B
2008/05/19Room:4-BRack:B
2008/03/17Room:4-BRack:B
2008/01/14Room:4-BRack:B
2007/11/12Room:4-BRack:B
2007/09/18Room:4-BRack:B
2007/07/17Room:4-BRack:B

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
FasFas (TNF receptor superfamily member)19Fas<tm1Osa>targeted mutation 1, Osaka University Medical School

Gene symbolGene nameChr.Allele symbolAllele namePromoter
lacZbeta-galactosidase (E. coli)19

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)19mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAmouse Fas genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, E. coli lacZ
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nature Genetics, 11, 294-300 (1995).RECIPIENT may only use the BIOLOGICAL RESOURCE for non-commercial academic research purpose.
The RECIPIENT should negotiate with the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE.
DepositorShigekazu Nagata (Kyoto University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

No Data