Strain Information | |
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Image | |
BRC No. | RBRC01418 |
Type | Spontaneous Mutation Congenic |
Species | Mus musculus |
Strain name | C3.HR1-Hr<hr>/Rbrc |
Former Common name | |
H-2 Haplotype | |
ES Cell line | |
Background strain | C3H/HeNCrlCrlj |
Appearance | agouti [A/A B/B C/C hr/+] agouti without hair [A/A B/B C/C hr/hr] |
Strain development | Four congenic strains of the Hr gene have been generated using Hos:HR-1 mice as the donor strain by successive backcrossing to C57BL/6JJcl (RBRC01223), BALB/cAnNMs (RBRC01417), C3H/HeNCrlj (RBRC01418) and MSM/MsRbrc (RBRC01222) strains as recipients at Experimental Animal Division, RIKEN BioResource Center (BRC). The deposition of the four congenic strains to RIKEN BRC has been acknowledged by HOSHINO LABORATORY ANIMALS, CORP. (Masayuki Hoshino, President). |
Strain description | |
Colony maintenance | Homozygote x Wild-type [C3H/HeNCrlCrlj] (Corss-Intercross Breeding) |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Hr | lysine demethylase and nuclear receptor corepressor | 14 | Hr | hairless |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | more 10 phenotypes |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | |
Research application | Cancer Research Cell Biology Research Dermatology Research Genetics Research Metabolism Research Mouse Models for Human Disease Toxicology Research |
Specific Term and Conditions | 1) The BIOLOGICAL RESOURCE shall be used only for academic research purposes by a not-for-profit organization. 2) The RECIPIENT must negotiate with RIKEN BRC and HOSHINO LABORATORY ANIMALS, CORP. and acquire a prior written consent to filing an application for a patent, or intellectual property or other rights based on the research results using the BIOLOGICAL RESOURCE. 3) The RECIPIENT of a for-profit organization must negotiate with HOSHINO LABORATORY ANIMALS, CORP. and obtain a prior written approval to use the BIOLOGICAL RESOURCE. 4) The RECIPIENT agrees that RIKEN BRC informs biannually to HOSHINO LABORATORY ANIMALS, CORP. of RECIPIENT organization name and quantity of distributed animals. |
Depositor | Atsushi Yoshiki (RIKEN) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- Mouse of the Month Nov 2011 |
BRC mice in Publications |
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No Data |