RBRC01377

Information1

Image
BRC No.RBRC01377
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameICR.Cg-Meox1<tm1(cre)Ysa>/YsaRbrc
Former Common nameMox1-cre
H-2 Haplotype
ES Cell line
Background strainICR
Appearancealbino [c/c]
Strain developmentDeveloped by Dr. Yumiko Saga (2004). This strain were maintained under ICR background.
Strain descriptionICR.Cg-Meox1<tm>. The Meox1 gene is a homeobox family gene, require for meterminig anterioposterior regionalization of mesoderm and in somite differentiation. In this mutant mouse, A cre recombinase gene was inserted in Mox1 gene.
Colony maintenanceHomozygtote x Heterozygote or Crossing to ICR (Jcl:MCH)
ReferencesDevelopment, 133(13): 2517-2525 (2006). 16728472

Health Report

Examination Date / Room / Rack2006/04/25Room:4-3Rack:B

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Meox1mesenchyme homeobox 111Meox1<tm1(cre)Ysa>targeted mutation 1, Yumiko Saga

Gene symbolGene nameChr.Allele symbolAllele namePromoter
crePhage P1 Cre recombinase11cre

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP11loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP11loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)11mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAphage P1 Cre recombinase, poly A, Phage P1 loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, bovine GH poly A, mouse Mox1 genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Development, 133, 2517-2525 (2006).
DepositorYumiko Saga (National Institute of Genetics)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Saga Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

No Data