RBRC01342

Information1

Image
BRC No.RBRC01342
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameEmx1-Cre Tg1
Former Common nameEmx1-Cre Tg1
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Takuji Iwasato and Shigeyoshi Itohara, RIKEN Brain Science Institute. The transgene was injected into the pronuclei of C57BL/6 fertilized eggs. C57BL/6 background.
Strain descriptionEmx1-Cre transgenitc mice, containing a transcriptional unit of a dorsal telencephalon specific promoter (Emx1 promoter) and Cre recombinase gene. Line 1 (RBRC01342), Line 2 (RBRC01343) and Line 3 (RBRC01344). The most suitable cre driver strain is Emx1-cre delta neo knock-in mice (RBRC01345) (no ectopic cre expression is detected).
Colony maintenanceCarrier x Noncarrier [C57BL/6JJcl]
ReferencesGenesis, 38, 130-138 (2004). 15048810

Health Report

Examination Date / Room / Rack2018/09/25Room:4-ARack:F
2018/07/30Room:4-ARack:F
2009/11/16Room:4-ARack:D
2009/09/14Room:4-ARack:D
2009/07/13Room:4-ARack:D
2009/05/19Room:4-ARack:D
2009/05/18Room:4-ARack:D
2009/03/16Room:4-ARack:D

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
crePhage P1 Cre recombinaseUNcremouse Emx1 (Drosophila homeobox gene empty spiracles (Ems) mouse homolog) promoter, SV40 poly A

Gene symbolGene nameChr.Allele symbolAllele namePromoter
nlsSV40 large T antigen nuclear localization signal (NLS)UNnls

Information2

Donor DNAmouse Emx1 (Drosophila homeobox gene empty spiracles (Ems) mouse homolog) promoter, Simian virus 40 Large T antigen nuclear localization signal (NLS), phage P1 Cre recombinase, SV40 poly A
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genesis, 38, 130-138 (2004).
DepositorShigeyoshi Itohara (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-
Mouse of the Month June 2006

BRC mice in Publications

Chen CM, Wang HY, You LR, Shang RL, Liu FC.
Expression analysis of an evolutionarily conserved metallophosphodiesterase gene, Mpped1, in the normal and beta-catenin-deficient malformed dorsal telencephalon.
Dev. Dyn. 239(6) 1797-806(2010) 20503375