RBRC01272

Information1

Image
BRC No.RBRC01272
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameBALB/c-elap/Rbrc
Former Common nameelap mouse
H-2 Haplotype
ES Cell line
Background strainBALB/c
Appearancealbino [A/A b/b c/c]
Strain developmentDeveloped by Dr. Sunao Aso at Chemical Inspection and Testing Iinstitute, Japan.
Strain descriptionEye lens aplasia. Autosomal recessive mutation which arose in the BALB/c breeding colony. Homozygous mutant mice for eye lens aplasia have microphthalmia, aphakia, absence of the anterior chamber, dystrophy of the cornea and vitreous body, and retinal disorganization.
Colony maintenanceSibling MatingHomozygous mutant mice are viable and fertile.
ReferencesTeratology, 61, 262-272 (2000). 10716744
Exp. Anim., 50, 97-98 (2001). 11326432
Lab. Anim. Sci., 45, 41-46 (1995). 7752613
Teratology, 58, 44-53 (1998). 9787405

Health Report

Examination Date / Room / Rack2009/11/09Room:4-6Rack:B
2009/09/07Room:4-6Rack:B
2009/07/06Room:4-6Rack:B
2009/05/12Room:4-6Rack:B
2009/05/11Room:4-6Rack:B
2009/03/09Room:4-6Rack:B
2008/12/15Room:3-ARack:B
2008/10/20Room:3-ARack:B

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
elapeye lens aplasia2elap<elap>eye lens aplasia

Information2

Donor DNA
Research applicationCancer Research
Cell Biology Research
Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorSunao Aso (Chemicals Evaluation and Research Institute)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data