Information1 | |
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Image | |
BRC No. | RBRC01235 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | STOCK Ptpro<tm1Shs>/Rbrc |
Former Common name | Glepp1-KO, Glepp1 Knockout mice |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | black (a/a B/B C/C) |
Strain development | Developed by Dr. Takuya Tomemori at Tokyo Metropolitan Institute of Gerontology in 2001. |
Strain description | The Glepp1 (Ptpro) gene is a receptor tyrosine phsophatase that is present on the surface of the glomerular podocyte and plays in regulating podocyte structure and function. Homozygous mutant mice are viable and fertile. |
Colony maintenance | Sibling Mating (Homozygote x Homozygote) |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Ptproprotein tyrosine phosphatase, receptor type, O6Ptpro<tm1Shs>targeted mutation 1, Takuji ShirasawaGlepp1 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)6neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) |
Information2 | |
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Donor DNA | phage P1 loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse Glepp1 genomic DNA[update Oct., 20, 2014] |
Research application | Cell Biology Research Cre/loxP system |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. |
Depositor | Takuji Shirasawa (Tokyo Metropolitan Institute of Gerontology) |
Strain Status | ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Yu, Yang. Regulation of retinal axonal projections by the R3 receptor-like protein tyrosine phosphatase subfamily in mice. SOKENDAI (The Graduate University for Advanced Studies) (2018) |