RBRC01221

Information1

Image
BRC No.RBRC01221
TypeInbred
SpeciesMus musculus
Strain nameSM/J
Former Common name
H-2 Haplotype
ES Cell line
Background strainSM
Appearancewhite-bellied agouti [A<w>/a]
black [a/a]
Strain developmentDeveloped by MacArthur in 1939. The SM/J strain was produced by crossing seven inbred strains including DBA and selecting for small body size. This strain was introduced to National Institute of Genetics from the Jackson laboratory in 1985, subsequently maintained by Dr. Masahiko Nishimura at Hamamatsu University School of Medicine, and then Nagoya University.
Strain descriptionThe SM/J strain is segregating inbred strain for the agouti alleles white-bellied agouti (A<w>) and black (a). Developed by MacArthur in 1939. These mice are susceptible to diet-induced atherosclerosis and obesity without diabetes. The body size is small at birth and weaning, but attain a normal body weight as the animals mature.
Colony maintenanceSibling mating (white-bellied agouti x black)
ReferencesBiosci Biotechnol Biochem, 70(3): 677-683 (2006). 16556985
Biosci Biotechnol Biochem, 68(1):226-230 (2004). 14745189
Exp Anim, 49(3):217-224 (2000). 11109545
Exp Anim, 52(5):415-417 (2003). 12638235
Exp Anim, 58(4): 357-361 (2009). 19654433
Diabetes, 52(1):180-186 (2003). 12502510
Exp Anim, 49(2):83-90 (2000). 10889946
J Nutr Sci Vitaminol, 55(3): 257-263 (2009). 19602834
Immunogenetics, 65(1):17-24 (2013). 23081743
Physiol Genomics, 35(1): 65-74 (2008). 18628340
Immunogenetics, 53(10-11):925-929 (2002). 11862393
Mamm Genome, 23(11-12):764-769 (2012). 23052825
Exp Anim, 50(4):319-324 (2001). 11515095
J Lipid Res, 51(12): 3463-3469 (2010). 20802160
J Lipid Res, 48(9): 2039-2046 (2007). 17595448
Exp Anim, 52(1):37-42 (2003). 12638235
Parasitol Int, 49(4):335-338 (2000). 11077268
Diabetologia, 49(3):486-495 (2006). 16447060

Health Report

Examination Date / Room / Rack2019/04/01Room:3-5Rack:D
2019/02/04Room:3-5Rack:D
2018/12/03Room:3-5Rack:D
2018/10/01Room:3-5Rack:D
2018/08/06Room:3-5Rack:D
2018/06/04Room:3-5Rack:D
2018/04/02Room:3-5Rack:D
2018/02/05Room:3-5Rack:D

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
null

Information2

Donor DNA
Research applicationGenetics Research
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorMasahiko Nishimura (Nagoya University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.

BRC mice in Publications

Kobayashi M, Ohno T, Kawada T, Ikegami H, Nishimura M, Horio F.
Serum adiponectin concentration: its correlation with diabetes-related traits and quantitative trait loci analysis in mouse SMXA recombinant inbred strains.
Biosci. Biotechnol. Biochem. 70(3) 677-83(2006) 16556985

Kobayashi M, Io F, Kawai T, Kumazawa M, Ikegami H, Nishimura M, Ohno T, Horio F.
Major quantitative trait locus on chromosome 2 for glucose tolerance in diabetic SMXA-5 mouse established from non-diabetic SM/J and A/J strains.
Diabetologia 49(3) 486-95(2006) 16447060

Shigeko Kijimoto-Ochiai, Tokuko Matsumoto-Mizuno, Daisuke Kamimura, Masaaki Murakami, Miwako Kobayashi, Ichiro Matsuoka, Hiroshi Ochiai, Hideharu Ishida, Makoto Kiso, Keiko Kamimura, Toshiaki Koda.
NEU1 sialidase exists on the cell surface of the mouse thymocyte and CD5 is a natural substrate for it.
Glycobiology 28(5) 306-317(2018) 29897583

Kijimoto-Ochiai S, Koda T, Suwama T, Matsukawa H, Fujii M, Tomobe K, Nishimura M.
Low expression of Neu2 sialidase in the thymus of SM/J mice-existence of neuraminidase positive cells Neu-medullocyte in the murine thymus.
Glycoconj. J. 25(8) 787-96(2008) 18553168

Kumazawa M, Kobayashi M, Io F, Kawai T, Nishimura M, Ohno T, Horio F.
Searching for genetic factors of fatty liver in SMXA-5 mice by quantitative trait loci analysis under a high-fat diet.
J. Lipid Res. 48(9) 2039-46(2007) 17595448