Strain Data Sheet



BRC No.RBRC01221
SpeciesMus musculus
Strain nameSM/J
Former Common name
H-2 Haplotype
ES Cell line
Background strainSM
Appearancewhite-bellied agouti [A<w>/a]
black [a/a]
Strain developmentDeveloped by MacArthur in 1939. The SM/J strain was produced by crossing seven inbred strains including DBA and selecting for small body size. This strain was introduced to National Institute of Genetics from the Jackson laboratory in 1985, subsequently maintained by Dr. Masahiko Nishimura at Hamamatsu University School of Medicine, and then Nagoya University.
Strain descriptionThe SM/J strain is segregating inbred strain for the agouti alleles white-bellied agouti (A<w>) and black (a). Developed by MacArthur in 1939. These mice are susceptible to diet-induced atherosclerosis and obesity without diabetes. The body size is small at birth and weaning, but attain a normal body weight as the animals mature.
Colony maintenanceSibling mating (white-bellied agouti x black)
ReferencesParasitol Int, 49(4):335-338 (2000). 11077268
Exp Anim, 52(1):37-42 (2003). 12638235
Immunogenetics, 53(10-11):925-929 (2002). 11862393
Exp Anim, 58(4): 357-361 (2009). 19654433
J Lipid Res, 51(12): 3463-3469 (2010). 20802160
Diabetologia, 49(3):486-495 (2006). 16447060
Mamm Genome, 23(11-12):764-769 (2012). 23052825
J Nutr Sci Vitaminol, 55(3): 257-263 (2009). 19602834
Diabetes, 52(1):180-186 (2003). 12502510
Biosci Biotechnol Biochem, 70(3): 677-683 (2006). 16556985
Exp Anim, 50(4):319-324 (2001). 11515095
Immunogenetics, 65(1):17-24 (2013). 23081743
Physiol Genomics, 35(1): 65-74 (2008). 18628340
Exp Anim, 49(2):83-90 (2000). 10889946
Exp Anim, 49(3):217-224 (2000). 11109545
Biosci Biotechnol Biochem, 68(1):226-230 (2004). 14745189
J Lipid Res, 48(9): 2039-2046 (2007). 17595448
Exp Anim, 52(5):415-417 (2003). 12638235

Health Report

Examination Date / Room / Racknull


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter


Donor DNA
Research applicationGenetics Research
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorMasahiko Nishimura (Nagoya University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

Kobayashi M, Ohno T, Kawada T, Ikegami H, Nishimura M, Horio F.
Serum adiponectin concentration: its correlation with diabetes-related traits and quantitative trait loci analysis in mouse SMXA recombinant inbred strains.
Biosci Biotechnol Biochem 70(3) 677-83(2006) 16556985

Kobayashi M, Io F, Kawai T, Kumazawa M, Ikegami H, Nishimura M, Ohno T, Horio F.
Major quantitative trait locus on chromosome 2 for glucose tolerance in diabetic SMXA-5 mouse established from non-diabetic SM/J and A/J strains.
Diabetologia 49(3) 486-95(2006) 16447060

Kijimoto-Ochiai S, Matsumoto-Mizuno T, Kamimura D, Murakami M, Kobayashi M, Matsuoka I, Ochiai H, Ishida H, Kiso M, Kamimura K, Koda T.
Existence of NEU1 sialidase on mouse thymocytes whose natural substrate is CD5.
Glycobiology 28(5) 306-317(2018) 29897583

Kijimoto-Ochiai S, Koda T, Suwama T, Matsukawa H, Fujii M, Tomobe K, Nishimura M.
Low expression of Neu2 sialidase in the thymus of SM/J mice-existence of neuraminidase positive cells Neu-medullocyte in the murine thymus.
Glycoconj J 25(8) 787-96(2008) 18553168

Kumazawa M, Kobayashi M, Io F, Kawai T, Nishimura M, Ohno T, Horio F.
Searching for genetic factors of fatty liver in SMXA-5 mice by quantitative trait loci analysis under a high-fat diet.
J Lipid Res 48(9) 2039-46(2007) 17595448

Kasahara T, Abe K, Mekada K, Yoshiki A, Kato T.
Genetic variation of melatonin productivity in laboratory mice under domestication.
Proc Natl Acad Sci U S A 107(14) 6412-7(2010) 20308563