RBRC01200

Information1

Image
BRC No.RBRC01200
TypeTransgene CongenicCartagena
SpeciesMus musculus
Strain nameNZW.C3-Tg(Mt1-Il5)6Ato
Former Common nameNZW.IL-5
H-2 Haplotype
ES Cell line
Background strainNZW
Appearancealbino [b/b c/c p/p]
Strain developmentGenerated by Kiyoshi Takatsu, Kumamoto University Medical School. The transgene was injected into the pronuclei of C3H fertilized eggs. C57BL/6 (RBRC01908) and BALB/c (RBRC05910) background (Developed by Institute of Medical Science, University of Tokyo), NZW background (RBRC01200) (Developed by Juntendo University School of Medicine).
Strain descriptionMt1-Il5 transgenic mice. These transgenic mice express mouse IL-5 under the control of the Mt1 promoter.
Colony maintenanceCarrier x Noncarrier [or Crossing to NZW/NSlc] Tg mice show no obvious abnormality.
ReferencesJ. Exp. Med., 173, 429-437 (1991). 1988543
Eur. J. immunol., 34, 2740-2749 (2004). 15368290

Health Report

Examination Date / Room / Rack2006/04/04Room:3-5Rack:B
2006/01/30Room:3-5Rack:B
2005/11/29Room:3-5Rack:B
2005/10/04Room:3-5Rack:B
2005/07/05Room:3-5Rack:B

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Il5interleukin 5UNIl5mouse metallothionein promoter, rabbit beta-globin

Gene symbolGene nameChr.Allele symbolAllele namePromoter
HBB2rabbit beta-globin splice donorUNHBB2

Gene symbolGene nameChr.Allele symbolAllele namePromoter
HBB2rabbit beta-globin splice acceptorUNHBB2

Information2

Donor DNAmouse metallothionein promoter, rabbit beta-globin SD, rabbit beta-globin SA, mouse IL5 cDNA, rabbit beta-globin polyA, SV40 polyadenylation site
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Eur. J. Immunol., 34, 2740-2749 (2004).
DepositorSachiko Hirose (Juntendo University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data