Strain Data Sheet

RBRC01178

Strain Information

Image
BRC No.RBRC01178
TypeRecombinant Inbred
SpeciesMus musculus
Strain nameSMXA-5
Former Common name
H-2 Haplotype
ES Cell line
Background strainSM, A
Appearancebrown [a/a b/b C/C]
Strain developmentDeveloped by Dr. Masahiko Nishimura, Nagoya University. Parental strains are SM/J and A/J.
Strain descriptionSMXA Recombinant Inbred (RI) strains were developed and deposited by Dr. Masahiko Nishimura, Nagoya University. Parental strains are SM/J and A/J. This strain set is useful for the quantitative trait loci mapping, a segregation analysis and a linkage mapping.
Colony maintenanceSibling Mating
References
SMXA-5 mouse as a diabetic model susceptible to feeding a high-fat diet.
Kobayashi M, Io F, Kawai T, Nishimura M, Ohno T, Horio F
Biosci Biotechnol Biochem, 68(1):226-230 (2004). 14745189

Detection of loci for allergic asthma using SMXA recombinant inbred strains of mice.
Ohno T, Okamoto M, Hara T, Hashimoto N, Imaizumi K, Matsushima M, Nishimura M, Shimokata K, Hasegawa Y, Kawabe T
Immunogenetics, 65(1):17-24 (2013). 23081743

Major quantitative trait locus on chromosome 2 for glucose tolerance in diabetic SMXA-5 mouse established from non-diabetic SM/J and A/J strains.
Kobayashi M, Io F, Kawai T, Kumazawa M, Ikegami H, Nishimura M, Ohno T, Horio F
Diabetologia, 49(3):486-495 (2006). 16447060

Quantitative trait locus analysis of serum insulin, triglyceride, total cholesterol and phospholipid levels in the (SM/J x A/J)F2 mice.
Anunciado R V, Nishimura M, Mori M, Ishikawa A, Tanaka S, Horio F, Ohno T, Namikawa T
Exp Anim, 52(5):415-417 (2003). 12638235

Searching for genetic factors of fatty liver in SMXA-5 mice by quantitative trait loci analysis under a high-fat diet.
Kumazawa M, Kobayashi M, Io F, Kawai T, Nishimura M, Ohno T, Horio F
J Lipid Res, 48(9): 2039-2046 (2007). 17595448

Serum adiponectin concentration: its correlation with diabetes-related traits and quantitative trait loci analysis in mouse SMXA recombinant inbred strains.
Kobayashi M, Ohno T, Kawada T, Ikegami H, Nishimura M, Horio F
Biosci Biotechnol Biochem, 70(3): 677-683 (2006). 16556985

Characterization of hyperinsulinemic recombinant inbred (RI) strains (SMXA-5 and SMXA-9) derived from normoinsulinemic SM/J and A/J mice.
Anunciado R V, Horio F, Ohno T, Tanaka S, Nishimura M, Namikawa T
Exp Anim, 49(2):83-90 (2000). 10889946

Genetic analysis of mortality in murine angiostrongyliasis costaricensis using SMXA recombinant inbred mouse strains.
Ishih A, Ohno T, Nishimura M, Terada M
Parasitol Int, 49(4):335-338 (2000). 11077268

Distribution of body weight, blood insulin and lipid levels in the SMXA recombinant inbred strains and the QTL analysis.
Anunciado R V, Ohno T, Mori M, Ishikawa A, Tanaka S, Horio F, Nishimura M, Namikawa T
Exp Anim, 49(3):217-224 (2000). 11109545

Combinations of nondiabetic parental genomes elicit impaired glucose tolerance in mouse SMXA recombinant inbred strains.
Kobayashi M, Ohno T, Tsuji A, Nishimura M, Horio F
Diabetes, 52(1):180-186 (2003). 12502510

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • hyperglycemia(MP:0001559)

  • impaired glucose tolerance(MP:0005293)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorMasahiko Nishimura (Nagoya University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Mouse of the Month Nov 2005

    BRC mice in Publications

    No Data