Strain Information | |
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Image | |
BRC No. | RBRC01100 |
Type | Transgene |
Species | Mus musculus |
Strain name | B6.Cg-Tg(Ovgp1-TAg)1Imiy |
Former Common name | B6.Cg-Tg(Ovgp1-TAg)1Imiy; mogP-Taq Transgenic mouse; Mouse Transgenic for Murine Oviduct-Specific Glycoprotein Promoter-Driven Simian Virus 40 Large T-Antigen (mogp-Taq Transgenic Mouse) |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6 |
Appearance | |
Strain development | Developed by Ichiro Miyoshi and Noriyuki Kasai, Tohoku University Graduate School of Medicine in 2001. The transgene was injected into the pronuclei of B6D2F2 fertilized eggs. The mutant mice were crossed to C57BL/6. |
Strain description | mogp-Tag transgenic mice, expressing a simian virus 40 large T antigen (Tag) under the control of murine oviduct specific glycoprotein promoter (a 2.2-kb segment of the 5’-flanking sequence). Tg females develop severe uterine tumors by 6 weeks of age. Average life span of Tg males is around 6 months. |
Colony maintenance | Carrier (male) x Noncarrier (female) [C57BL/6JJcl] |
References | Mouse transgenic for murine oviduct-specific glycoprotein promoter-driven simian virus 40 large T-antigen: tumor formation and its hormonal regulation. Miyoshi I, Takahashi K, Kon Y, Okamura T, Mototani Y, Araki Y, Kasai N Mol. Reprod. Dev., 63,168-176 (2002). 12203826 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
HBB2 | rabbit beta-globin polyA | UN | HBB2 | ||||
TAg | SV40 Large T-Antigen | UN | TAg | Murine Oviduct-Specific Glycoprotein Promoter, rabbit beta-globin poly A |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | 5'-flanking region of Murine Oviduct-Specific Glycoprotein (mouse mogp-1), SV40 large T genomic DNA, rabbit beta-globin poly A |
Research application | Cancer Research Reproductive Biology Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mol. Reprod. Dev., 63,168-176 (2002). The DEPOSITOR should be a co-author in articles when the RECIPIENTs publish their data using these mice for 2 year after provided to the RIKEN BRC. |
Depositor | Noriyuki Kasai (Tohoku University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |