RBRC01100

Information1

Image
BRC No.RBRC01100
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6.Cg-Tg(Ovgp1-TAg)1Imiy
Former Common nameB6.Cg-Tg(Ovgp1-TAg)1Imiy; mogP-Taq Transgenic mouse; Mouse Transgenic for Murine Oviduct-Specific Glycoprotein Promoter-Driven Simian Virus 40 Large T-Antigen (mogp-Taq Transgenic Mouse)
H-2 Haplotype
ES Cell line
Background strainC57BL/6
Appearance
Strain developmentDeveloped by Ichiro Miyoshi and Noriyuki Kasai, Tohoku University Graduate School of Medicine in 2001. The transgene was injected into the pronuclei of B6D2F2 fertilized eggs. The mutant mice were crossed to C57BL/6.
Strain descriptionmogp-Tag transgenic mice, expressing a simian virus 40 large T antigen (Tag) under the control of murine oviduct specific glycoprotein promoter (a 2.2-kb segment of the 5’-flanking sequence). Tg females develop severe uterine tumors by 6 weeks of age. Average life span of Tg males is around 6 months.
Colony maintenanceCarrier (male) x Noncarrier (female) [C57BL/6JJcl]
ReferencesMol. Reprod. Dev., 63,168-176 (2002). 12203826

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
HBB2rabbit beta-globin polyAUNHBB2

Gene symbolGene nameChr.Allele symbolAllele namePromoter
TAgSV40 Large T-AntigenUNTAgMurine Oviduct-Specific Glycoprotein Promoter, rabbit beta-globin poly A

Information2

Donor DNA5'-flanking region of Murine Oviduct-Specific Glycoprotein (mouse mogp-1), SV40 large T genomic DNA, rabbit beta-globin poly A
Research applicationCancer Research
Reproductive Biology Research
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Molecular Reproduction and Development, 63, 168-176 (2002).The DEPOSITOR should be a co-author in articles when the RECIPIENTs publish their data using these mice for 2 year after provided to the RIKEN BRC.
DepositorNoriyuki Kasai (Tohoku University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data