Strain Data Sheet



BRC No.RBRC00998
TypeTransgene CongenicCartagena
SpeciesMus musculus
Strain nameC57BL/6-TgN(muAqp0)4Tohm
Former Common nameTg4
H-2 Haplotype
ES Cell line
Background strainC57BL/6NCrSlc
Strain developmentDeveloped by Tadashi Okamura, Tohoku University Graduate School of Medicine in 2000.
Strain descriptionThese transgenic mice expressing Mip in the crystalline lens. These mice exhibit congenital cataracts, and it is easy to identify it from the surface. This strain may be useful for studying the onset of cataracts.
Colony maintenance
ReferencesGenomics, 81, 361-368 (2003). 12676560

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Mipmajor intrinsic protein of eye lens fiberUNMipchicken beta-B1 crystallin promoter, SV40 polyadenylation signal


Donor DNAchicken beta-B1 crystallin (Crybb1) promoter, mouse Aquaporin-0 cDNA, SV40 polyadenylation signal
Research application
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genomics, 81, 361-368 (2003). The RECIPIENT agrees to use the BIOLOGICAL RESOURCE only for publication of research papers.
DepositorTadashi Okamura (Tohoku University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data