Information1 | |
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Image | ![]() |
BRC No. | RBRC00998 |
Type | Transgene Congenic![]() |
Species | Mus musculus |
Strain name | C57BL/6-TgN(muAqp0)4Tohm |
Former Common name | Tg4 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6NCrSlc |
Appearance | black |
Strain development | Developed by Tadashi Okamura, Tohoku University Graduate School of Medicine in 2000. |
Strain description | These transgenic mice expressing Mip in the crystalline lens. These mice exhibit congenital cataracts, and it is easy to identify it from the surface. This strain may be useful for studying the onset of cataracts. |
Colony maintenance | |
References | Genomics, 81, 361-368 (2003). 12676560 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Mipmajor intrinsic protein of eye lens fiberUNMipchicken beta-B1 crystallin promoter, SV40 polyadenylation signal |
Information2 | |
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Donor DNA | chicken beta-B1 crystallin (Crybb1) promoter, mouse Aquaporin-0 cDNA, SV40 polyadenylation signal |
Research application | |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genomics, 81, 361-368 (2003). The RECIPIENT agrees to use the BIOLOGICAL RESOURCE only for publication of research papers. |
Depositor | Tadashi Okamura (Tohoku University) |
Strain Status | ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |