Strain Data Sheet

RBRC00996

Strain Information

Image
BRC No.RBRC00996
TypeSpontaneous Mutation Congenic
SpeciesMus musculus
Strain nameDDI-Mip<Cat-Tohm>/TohmRbrc
Former Common nameCataract Tohoku mice
H-2 Haplotype
ES Cell line
Background strain
Appearancealbino
Strain development
Strain description
Colony maintenance
References
Bilateral congenital cataracts result from a gain-of-function mutation in the gene for aquaporin-0 in mice.
Tadashi Okamura, Ichiro Miyoshi, Kazuhiro Takahashi, Yasumasa Mototani, Sadao Ishigaki, Yasuhiro Kon, Noriyuki Kasai
Genomics, 81, 361-368 (2003). 12676560

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Mip
MGI:96990		major intrinsic protein of lens fiber10Mip<Cat-Tohm>
MGI:2657065		dominatnt cataract Tohoku
  • cataract 15 multiple types(DisGeNET, MedGEN)

    • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal lens epithelium morphology (MP:0003237)

  • abnormal lens fiber morphology (MP:0002840)

  • cataract (MP:0001304)

  • developmental cataract (MP:0031345)

  • microphthalmia (MP:0001297)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genomics, 81, 361-368 (2003).
    DepositorTadashi Okamura (Tohoku University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data