BRC No.RBRC00787
SpeciesMus musculus
Strain nameC57BL/6-Tg(GOFMBD)5Imeg
Former Common nameOct-MBDGFP#5, TgN(GOFMBD)5Imeg
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Strain developmentDeveloped by Kuniya Abe, RIKEN BioResrouce Center (Institute of Molecular Embryology and Genetics) in 2001.
Strain descriptionGOFMBD transgenic mice expressing MBD (methylated DNA bifing domain) and GFP fusion protein under the control of the Oct-4 promoter (GOF18). GODMBD lines containing a proximal enhancer (PE): Line 1, Line 2, Line 4, Line 5. deltaMBD lines lacking a proximal enhancer (PE): Line 1 (RBRC00788), Line 2 (RBRC00789), Line 3 (RBRC00790).
Colony maintenanceCarrier x Carrier [or Crossing to C57BL/6JJcl]

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
GFPGreen Fluorescent Protein (Jellyfish)UNOct 3/4 promoter

Gene symbolGene nameChr.Allele symbolAllele namePromoter
MBD (methylated DNA binding domain)UN


Donor DNAOct3/4 promoter, MBD(methylated DNA binding domain) cDNA, Jellyfish GFP cDNA
Research applicationCell Biology Research
Developmental Biology Research
Fluorescent Proteins/lacZ System
Genetics Research
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. The DEPOSITOR should be a co-author in articles when the users publish their data using these mice for 2 year after provided to the RIKEN BRC.
Users should contact the DEPOSITOR in the case of application for any patents with the results from these mice.
DepositorKuniya Abe (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC's MTA. Please also read Schedule B.
Lab HP

BRC mice in Publications

No Data