Strain Data Sheet
RBRC00755
Information1 | |
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| Image | |
| BRC No. | RBRC00755 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6;129P2-Fcer2a<tm1Kik>/KikRbrc |
| Former Common name | CD23 Knockout mice |
| H-2 Haplotype | |
| ES Cell line | E14.1 [129P2/OlaHsd] |
| Background strain | |
| Appearance | |
| Strain development | Developed by Research Institute, Osaka Medical Center for Maternal and Child Health. |
| Strain description | |
| Colony maintenance | |
| References | J. Immunol., 147, 1067-1074 (1991). 1861070 Proc. Natl. Acad. Sci. USA, 91, 6835-6939 (1994). 8041705 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Fcer2aFc receptor, IgE, low affinity II, alpha polypeptide8Fcer2a<tm1Kik>targeted mutation 1, Hitoshi KikutaniCD23, FC epsilon RII, Fce2, low-affinity IgE receptor, Ly-42 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)8neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Information2 | |
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| Donor DNA | herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, HSV tk poly A (pMC1 neo-poly A GenBank:U43612), mouse CD23 genomic DNA |
| Research application | Immunology and Inflammation Research |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc. Natl. Acad. Sci. USA, 91, 6835-6839 (1994). |
| Depositor | Hitoshi Kikutani (Osaka University) |
| Strain Status |  Frozen embryos |
| Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
| Additional Info. | Genetic Background Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Obayashi K, Doi T, Koyasu S. Dendritic cells suppress IgE production in B cells. Int Immunol 19(2) 217-26(2007) 17208926 |