Strain Data Sheet

RBRC00755

Information1

Image
BRC No.RBRC00755
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Fcer2a<tm1Kik>/KikRbrc
Former Common nameCD23 Knockout mice
H-2 Haplotype
ES Cell lineE14.1 [129P2/OlaHsd]
Background strain
Appearance
Strain developmentDeveloped by Research Institute, Osaka Medical Center for Maternal and Child Health.
Strain description
Colony maintenance
ReferencesJ. Immunol., 147, 1067-1074 (1991). 1861070
Proc. Natl. Acad. Sci. USA, 91, 6835-6939 (1994). 8041705

Health Report

Examination Date / Room / Racknull

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Fcer2aFc receptor, IgE, low affinity II, alpha polypeptide8Fcer2a<tm1Kik>targeted mutation 1, Hitoshi KikutaniCD23, FC epsilon RII, Fce2, low-affinity IgE receptor, Ly-42

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)8neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Information2

Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, HSV tk poly A (pMC1 neo-poly A GenBank:U43612), mouse CD23 genomic DNA
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc. Natl. Acad. Sci. USA, 91, 6835-6839 (1994).
DepositorHitoshi Kikutani (Osaka University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Genetic Background
Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

Obayashi K, Doi T, Koyasu S.
Dendritic cells suppress IgE production in B cells.
Int Immunol 19(2) 217-26(2007) 17208926