RBRC00755

Information1

Image
BRC No.RBRC00755
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Fcer2a<tm1Kik>/KikRbrc
Former Common nameCD23 Knockout mice
H-2 Haplotype
ES Cell lineE14.1 [129P2/OlaHsd]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
ReferencesProc. Natl. Acad. Sci. USA, 91, 6835-6939 (1994). 8041705
J. Immunol., 147, 1067-1074 (1991). 1861070

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Fcer2aFc receptor, IgE, low affinity II, alpha polypeptide8Fcer2a<tm1Kik>targeted mutation 1, Hitoshi Kikutani

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)8herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Information2

Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, HSV tk poly A (pMC1 neo-poly A GenBank:U43612), mouse CD23 genomic DNA
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc. Natl. Acad. Sci. USA, 91, 6835-6839 (1994).
DepositorHitoshi Kikutani (Osaka University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-
Genetic Background

BRC mice in Publications

Obayashi K, Doi T, Koyasu S.
Dendritic cells suppress IgE production in B cells.
Int. Immunol. 19(2) 217-26(2007) 17208926