Strain Data Sheet


Strain Information

BRC No.RBRC00639
SpeciesMus musculus molossinus
Strain nameJF1/Msf
Former Common nameJapanese Fancy 1
H-2 Haplotype
ES Cell line
Background strainJF1 [Mus musculus molossinus]
Appearanceblack spotted white coat, black eyes [a/a B/B C/C D/D s/s]
Strain developmentThe JF1/Ms strain was derived from fancy mice purchased at a market in Denmark in 1987, and has been maintained at the National Institute of Genetics, Mishima, Japan. In 1993, it was established as inbred strain and was named JF1, Japanese Fancy mouse 1.
Strain descriptionMorphological and genetical analysis indicated that the JF1 mice originated from the Japanese wild mice, Mus musculus molossinus. The coat color of this strain is black spotted white coat with black eyes. The related genes are a/a B/B C/C D/D s/s.
Colony maintenanceSibling MatingFemales are able to get pregnant after 3 months old.
ReferencesMamm. Genome, 9, 15-19 (1998). 9434939
Genome Res., 23(8), 1329-1338 (2013). 23604024

Health Report

Examination Date / Room / Rack2024/04/22Room:3-CRack:L


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ednrbendothelin receptor type B14Ednrb<s>piebald

Ordering Information

Donor DNA
Research applicationGenetics Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genome Res., 23, 1329-1338 (2013). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. (Contact info: Tsuyoshi Koide, Ph.D. <>, Mouse Genomics Resource Laboratory)
DepositorToshihiko Shiroishi (National Institute of Genetics)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved embryos (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

Kamimura S, Hatanaka Y, Hirasawa R, Matsumoto K, Oikawa M, Lee J, Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A.
Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer.
Biol Reprod 91(5) 120(2014) 25232016

Hasegawa A, Mochida K, Matoba S, Yonezawa K, Ohta A, Watanabe G, Taya K, Ogura A.
Efficient production of offspring from Japanese wild-derived strains of mice (Mus musculus molossinus) by improved assisted reproductive technologies.
Biol Reprod 86(5) 167, 1-7(2012) 22337332

Matoba S, Ogura A.
Generation of functional oocytes and spermatids from fetal primordial germ cells after ectopic transplantation in adult mice.
Biol Reprod 84(4) 631-8(2011) 21076079

Lee J, Kanatsu-Shinohara M, Ogonuki N, Miki H, Inoue K, Morimoto T, Morimoto H, Ogura A, Shinohara T.
Heritable imprinting defect caused by epigenetic abnormalities in mouse spermatogonial stem cells.
Biol Reprod 80(3) 518-27(2009) 19020300

Matsuzaki H, Miyajima Y, Fukamizu A, Tanimoto K.
Orientation of mouse H19 ICR affects imprinted H19 gene expression through promoter methylation-dependent and -independent mechanisms.
Commun Biol 4(1) 1410(2021) 34921234

Hirose M, Hada M, Kamimura S, Matoba S, Honda A, Motomura K, Ogonuki N, Shawki HH, Inoue K, Takahashi S, Ogura A.
Aberrant imprinting in mouse trophoblast stem cells established from somatic cell nuclear transfer-derived embryos.
Epigenetics 13(7) 693-703(2018) 30079806

Matsuzaki H, Kimura M, Morihashi M, Tanimoto K.
Imprinted DNA methylation of the H19 ICR is established and maintained in vivo in the absence of Kaiso.
Epigenetics Chromatin 17(1) 20(2024) 38840164

Matsuzaki H, Kuramochi D, Okamura E, Hirakawa K, Ushiki A, Tanimoto K.
Recapitulation of gametic DNA methylation and its post-fertilization maintenance with reassembled DNA elements at the mouse Igf2/H19 locus.
Epigenetics Chromatin 13(1) 2(2020) 31937365

Sasaki N, Yamauchi H, Tomohiro N, Agui T.
The telocentric tandem repeat at the p-arm is not conserved in Mus musculus subspecies.
Gene 513(1) 214-8(2013) 23116940

Hada M, Miura H, Tanigawa A, Matoba S, Inoue K, Ogonuki N, Hirose M, Watanabe N, Nakato R, Fujiki K, Hasegawa A, Sakashita A, Okae H, Miura K, Shikata D, Arima T, Shirahige K, Hiratani I, Ogura A.
Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells.
Genes Dev 36(1-2) 84-102(2022) 34992147

Kim JM, Ogura A.
Changes in allele-specific association of histone modifications at the imprinting control regions during mouse preimplantation development.
Genesis 47(9) 611-6(2009) 19530139

Inoue K, Ogonuki N, Yamamoto Y, Takano K, Miki H, Mochida K, Ogura A.
Tissue-specific distribution of donor mitochondrial DNA in cloned mice produced by somatic cell nuclear transfer.
Genesis 39(2) 79-83(2004) 15170692

Hara S, Takano T, Fujikawa T, Yamada M, Wakai T, Kono T, Obata Y.
Forced expression of DNA methyltransferases during oocyte growth accelerates the establishment of methylation imprints but not functional genomic imprinting.
Hum Mol Genet 23(14) 3853-64(2014) 24599402

Honda A, Hirose M, Inoue K, Hiura H, Miki H, Ogonuki N, Sugimoto M, Abe K, Kanatsu-Shinohara M, Kono T, Shinohara T, Ogura A.
Large-scale production of growing oocytes in vitro from neonatal mouse ovaries.
Int J Dev Biol 53(4) 605-13(2009) 19247970

Okayama T, Goto T, Toyoda A.
Assessing nest-building behavior of mice using a 3D depth camera.
J Neurosci Methods 251 151-7(2015) 26051553

Sasaki K, Hara S, Yamakami R, Sato Y, Hasegawa S, Kono T, Morohaku K, Obata Y.
Ectopic expression of DNA methyltransferases DNMT3A2 and DNMT3L leads to aberrant hypermethylation and postnatal lethality in mice.
Mol Reprod Dev 86(6) 614-623(2019) 30834655

Shinmen A, Honda A, Ohkawa M, Hirose M, Ogonuki N, Yuzuriha M, Miki H, Mochida K, Inoue K, Abe K, Ito M, Ogura A.
Efficient production of intersubspecific hybrid mice and embryonic stem cells by intracytoplasmic sperm injection.
Mol Reprod Dev 74(9) 1081-8(2007) 17290420

Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.
Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus.
PLoS One 9(12) e114305(2014) 25470728

Kasahara T, Abe K, Mekada K, Yoshiki A, Kato T.
Genetic variation of melatonin productivity in laboratory mice under domestication.
Proc Natl Acad Sci U S A 107(14) 6412-7(2010) 20308563

Obata Y, Wakai T, Hara S, Kono T.
Long exposure to mature ooplasm can alter DNA methylation at imprinted loci in non-growing oocytes but not in prospermatogonia.
Reproduction 147(1) H1-6(2014) 24123131

Imaizumi Y, Furutachi S, Watanabe T, Miya H, Kawaguchi D, Gotoh Y.
Role of the imprinted allele of the Cdkn1c gene in mouse neocortical development.
Sci Rep 10(1) 1884(2020) 32024956