|Former Common name||RLC/Stm|
|ES Cell line|
|Strain development||Spontaneous mutation originally arose in CXSN/A strain. The mutant mice were bred with a BALB/cHeA and then maintained by inbreeding.|
|Strain description||rlc, Rupture of Lens Cataract. Spontaneous recessive mutation arose in CXSN/A mice. The mutation as a deletion of 27 bp at the end of 15th of Dock5 gene.|
|References||Graefe's Arch. Clin. Exp. Ophthalmol., 238, 970-978 (2000). 11196360|
Exp. Eye Res., 64, 107-113 (1997). 9093026
Genomics, 36, 553-554 (1996). 8884285
|Examination Date / Room / Rack||null|
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
|Research application||Mouse Models for Human Disease|
|Specific Term and Conditions||No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)|
|Depositor||Yoshibumi Matsushima (Saitama Cancer Center)|
|Strain Status||Frozen embryos|
|Strain Availability||Recovered litters from cryopreserved embryos (2 to 4 months)|
Cryopreserved embryos (within 1 month)
|Additional Info.||Necessary documents for ordering:|
BRC mice in Publications
Hiai H, Tsuruyama T, Yamada Y.
Pre-B lymphomas in SL/Kh mice: a multifactorial disease model.
Cancer Sci 94(10) 847-50(2003) 14556656
Omi N, Kiyokawa E, Matsuda M, Kinoshita K, Yamada S, Yamada K, Matsushima Y, Wang Y, Kawai J, Suzuki M, Hayashizaki Y, Hiai H.
Mutation of Dock5, a member of the guanine exchange factor Dock180 superfamily, in the rupture of lens cataract mouse.
Exp Eye Res 86(5) 828-34(2008) 18396277