RBRC00357

Information1

Image
BRC No.RBRC00357
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC.Cg-Tnc<tm1Sia> Foxn1<nu>/Rbrc
Former Common nameBALB/cA-Tnc<tm1Sia>-nude; BALB/cA-TgH(Tnc)-Foxn1nu
H-2 Haplotype
ES Cell line
Background strainBALB/cA
Appearance
Strain developmentDeveloped by Dr. M. Kusakabe, Tsukuba Life Science Center, Institute of Physical and Chemical Research (RIKEN).
Strain descriptionC.Cg-Tnc<tm1Sia> Foxn1<nu>. Mice lacking tenascin C gene with a nude mutation. This strain is useful for studying the function of tenascin C in tumor proliferation and metastasis, neoangiogenesis, interoganizartional interation, and transplantation of human tumor.
Colony maintenance
ReferencesBiochem. Biophys. Res. Commun., 290, 1220-1227 (2002). 11811993
J. Comp. Neurol., 430, 485-500 (2001). 11169482
Invest. Ophthalmol. Visual. Sci., 40, 1071-1080 (1999). 10235540
Am. J. Pathol., 152, 1237-1245 (1998). 9588892
Exp. Mol. Pathol., 72, 186-195 (2002). 12009782
Genes Dev., 6, 1821-1831 (1992). 1383086
Biochem. Biophys. Res. Commun., 231, 356-359 (1997). 9070278
Gene, 104, 177-185 (1991). 1717349
22nd Congress of the International Association for Breast Cancer Research Athens, Greece 25-28 September, pp 197-201 (1998). 9863494
J. Neurosci., 15, 1971-1983 (1995). 7534342
Biochem. Biophys. Res. Commun., 221, 151-156 (1996). 8660327
J. Invest. Dermatol., 111, 930-935 (1998). 9856798
乳癌基礎研究, 5, 41-45 (1996).
乳癌基礎研究, 8, 26-31 (1999).
炎症, 15(5), 377-381 (1996).

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Foxn1forkhead box N111Foxn1<nu>nude

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Tnctenascin C4Tnc<tm1Sia>targeted mutation 1, Shinichi Aizawa

Gene symbolGene nameChr.Allele symbolAllele namePromoter
lacZbeta-galactosidase (E. coli)4

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)4mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAE. coli neo, lacZ, mouse tenascin genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter)
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Am. J. Pathol., 152, 1237-1245 (1998). J. Invest. Dermatol., 111, 930-935 (1998). Invest. Ophthalmol. Visual. Sci., 40, 1071-1080 (1999).
DepositorRIKEN BRC (RIKEN BRC)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data