Information1 | |
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Image | ![]() |
BRC No. | RBRC00213 |
Type | Wild-derived Inbred |
Species | Mus musculus musculus |
Strain name | PWK |
Former Common name | |
H-2 Haplotype | |
ES Cell line | |
Background strain | PWK [Mus musculus musculus] |
Appearance | agouti [A/A] |
Strain development | Deposited by Rosemary Elliott, Roswell Park Cancer Institute. |
Strain description | PWK is descended by sib mating from a single pair of mice of the subspecies Mus musculus musculus caught in 1974 in Lhotka, Czech Republic. F1 hybrid males between C57BL/6 and PWK were found to be sterile. |
Colony maintenance | Sibling x Sibling. |
References | Blood, 83, 3225-3231 (1994). 8193357 Genetics, 162, 831-840 (2002). 12399393 Cell, 63, 717-728 (1990). 2225073 Mamm. Genome, 13, 293-298 (2002). 12115031 Proc. Natl. Acad. Sci. USA, 89, 3232-3235 (1992). 1314381 Dev. Biol., 198, 266-276 (1998). 9659932 |
Health Report | |
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Examination Date / Room / Rack | 2023/02/27Room:4-CRack:B 2022/11/29Room:4-CRack:B 2022/08/29Room:4-CRack:B 2022/05/31Room:4-CRack:B 2022/03/15Room:4-CRack:B 2021/12/13Room:4-CRack:B 2021/09/13Room:4-CRack:B 2021/06/14Room:4-CRack:B 2021/03/29Room:4-CRack:B |
Gene | |
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Gene info |
Information2 | |
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Donor DNA | |
Research application | Cell Biology Research Developmental Biology Research Genetics Research Reproductive Biology Research |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Roswell Park Cancer Inst. (Roswell Park Cancer Inst.) |
Strain Status | ![]() ![]() ![]() |
Strain Availability | Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) Live mouse (3 to 6 months) |
Additional Info. | Click Here for Mouse genomic DNA (RIKEN DNA Bank) Necessary documents for ordering: |
BRC mice in Publications |
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Fujiwara K, Igarashi J, Irahara N, Kimura M, Nagase H. New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK. BMC Genet 8 39(2007) 17598916 Horii T, Yanagisawa E, Kimura M, Morita S, Hatada I. Epigenetic differences between embryonic stem cells generated from blastocysts developed in vitro and in vivo. Cell Reprogram 12(5) 551-63(2010) 20818993 Kayashima T, Yamasaki K, Joh K, Yamada T, Ohta T, Yoshiura K, Matsumoto N, Nakane Y, Mukai T, Niikawa N, Kishino T. Atp10a, the mouse ortholog of the human imprinted ATP10A gene, escapes genomic imprinting. Genomics 81(6) 644-7(2003) 12782135 Yamasaki Y, Kayashima T, Soejima H, Kinoshita A, Yoshiura K, Matsumoto N, Ohta T, Urano T, Masuzaki H, Ishimaru T, Mukai T, Niikawa N, Kishino T. Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air. Hum Mol Genet 14(17) 2511-20(2005) 16037066 Bamunusinghe D, Naghashfar Z, Buckler-White A, Plishka R, Baliji S, Liu Q, Kassner J, Oler AJ, Hartley J, Kozak CA. Sequence Diversity, Intersubgroup Relationships, and Origins of the Mouse Leukemia Gammaretroviruses of Laboratory and Wild Mice. J Virol 90(8) 4186-98(2016) 26865715 Komatsu S, Kiyosawa H, Yoshiki A, Okazaki Y, Yoshino M, Tomaru Y, Watanabe S, Muramatsu M, Kusakabe M, Hayashizaki Y. Identification of seven loci for static glucokinesis and dynamic glucokinesis in mice. Mamm Genome 13(6) 293-8(2002) 12115031 Hayashida K, Kohno S. Hybrid male sterility is caused by mitochondrial DNA deletion. Mol Biol Rep 36(6) 1365-9(2009) 18649010 Yamasaki-Ishizaki Y, Kayashima T, Mapendano CK, Soejima H, Ohta T, Masuzaki H, Kinoshita A, Urano T, Yoshiura K, Matsumoto N, Ishimaru T, Mukai T, Niikawa N, Kishino T. Role of DNA methylation and histone H3 lysine 27 methylation in tissue-specific imprinting of mouse Grb10. Mol Cell Biol 27(2) 732-42(2007) 17101788 Wang Y, Joh K, Masuko S, Yatsuki H, Soejima H, Nabetani A, Beechey CV, Okinami S, Mukai T. The mouse Murr1 gene is imprinted in the adult brain, presumably due to transcriptional interference by the antisense-oriented U2af1-rs1 gene. Mol Cell Biol 24(1) 270-9(2004) 14673161 Fujiwara K, Inagaki Y, Soma M, Ozaki T, Nagase H. Mapping of new skin tumor susceptibility loci by a phenotype-driven congenic approach. Oncol Lett 16(5) 6670-6676(2018) 30405807 Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A. Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One 9(12) e114305(2014) 25470728 Morita S, Horii T, Kimura M, Arai Y, Kamei Y, Ogawa Y, Hatada I. Paternal allele influences high fat diet-induced obesity. PLoS One 9(1) e85477(2014) 24416415 Morita S, Nakabayashi K, Kawai T, Hayashi K, Horii T, Kimura M, Kamei Y, Ogawa Y, Hata K, Hatada I. Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity. Sci Rep 6 21693(2016) 26868178 |