RBRC00072

Information1

Image
BRC No.RBRC00072
TypeInbred
SpeciesMus musculus
Strain nameBUS/Idr-Cdh23<+>/Rbrc
Former Common nameBUS/Idr-+/+
H-2 Haplotype
ES Cell line
Background strainKYF
Appearancecinammon
Strain developmentDeveloped by Satoshi Yonezawa, Institute for Developmental Research, Japan. Spontaneous mutation originally arosed in KYF/MsIdr-Jsr strain.
Strain descriptionbustling spontaneous mutation arose in Cdh23 gene. Homozygous mutant mice exhibit behavioral abnormalities such as hyperactivity, circling, head tossing and head tilting with vestibulocochlear defects. Viable and fertile, but it is difficult for homozygous female to nurse pups.
Colony maintenanceSibling x Sibling
ReferencesActa Otolaryngol. Suppl., 519, 286-293 (1995). 7610888
Human Mutation, 27, 88-97 (2006). 16281288
Acta Otolaryngol., 117, 20-24 (1997). 9039475
Hear. Res., 134, 116-122 (1999). 10452381
Acta Otolaryngol. (Stockh), 116, 409-416 (1996). 8790740

Health Report

Examination Date / Room / Rack2019/05/27Room:4-BRack:K
2019/03/25Room:4-BRack:K
2019/01/28Room:4-BRack:K
2018/11/26Room:4-BRack:K
2018/09/25Room:4-BRack:K
2018/07/30Room:4-BRack:K
2018/05/21Room:4-BRack:K
2018/03/26Room:4-BRack:K

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Cdh23cadherin 23 (otocadherin)10Cdh23<v-bus>bustling waltzer

Information2

Donor DNA
Research applicationNeurobiology Research
Sensorineural Research
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorSatoshi Yonezawa (Aichi Human Service Center)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.

BRC mice in Publications

No Data